Review of medicinal plant associated with antihyper-lipidermia

Eric Omo Irinmwinuwa 1, *, Prince Chiazor Unekwe 1, Joseph Oyindamola Olanrewaju 1 and Charles Cherechi Njoku 2

1 Department of Pharmacology and Therapeutics, Faculty of Medicine, College of Health Sciences, Nnamdi Azikiwe University, Nnewi Campus, Nigeria.
2 School of Nursing Umuahia, Abia Sate, Nigeria.
 
Review Article
Magna Scientia Advanced Research and Reviews, 2022, 05(02), 046–053
Article DOI: 10.30574/msarr.2022.5.2.0047
Publication history: 
Received on 18 June 2022; revised on 26 July 2022; accepted on 28 July 2022
 
Abstract: 
Hyperlipidemia is a common disease around the world which has affected both developed and developing countries, in this disease blood level of lipids is elevated more than normal range. Elevated lipids levels (cholesterol, fats, and triglyceride) predispose the patient to various serious and sometimes lethal complications such as cardiovascular disease, cerebral strokes, hepatic and renal dysfunction. This review emphasizes on some plants (extracts) having anti-cholesterol actions, including; Glycyrrhiza glabra,Legenaria siceraria,Medicago sativa,Curcuma longa,Syzygium cerasoideum, Leptopus Cordifolius Decne, Piper longum, Moringa oleifera, Zingiber officinale, Trigonella foenum-graecum, Carum carvi, Carica papaya, Gloriosa superba, Ficus religiosa, Eleucine coracana, Lycium europaeum and Hibiscus sabdariffa for anti-hyperlipidemic potential. increase in the levels of these lipoproteins like, triglycerides (TG), Total cholesterol (TC), Very low density lipoprotein (VLDL) and low-density lipoprotein (LDL)includes some mechanisms of actions of these medicinal plants observed in triton-x, cholesterol, high fat diet, Poloxamer-407, Dexamethasone and alloxan-induced in-vivo and in-vitro models. Additionally, this review gives proof to the fact that these medicinal plants can be used for the management and prophylaxis of hyperlipidermia, thus reducing complications associated with hyperlipidermia.
 
Keywords: 
Cholesterol; Hyperlipidemia; Medicinal plants; Lipids; Triglyceride
 
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