Knee osteoarthritis severity concerning neutrophil-lymphocyte ratio
Orthopedic Department, Al-Zahrawi Hospital, Misan Health Directorate, Ministry of Health/Environment, Misan, Iraq.
Research Article
Magna Scientia Advanced Research and Reviews, 2021, 02(02), 080–084
Article DOI: 10.30574/msarr.2021.2.2.0054
Publication history:
Received on 20 June 2021; revised on 25 July 2021; accepted on 27 July 2021
Abstract:
Osteoarthritis (OA) is a disease with a significant inflammatory component. Neutrophil-lymphocyte ratio (NLR) level is a marker to determine inflammation. The study aimed to evaluate the association between the severity of knee OA and NLR. A case-control study was conducted in Al-Zahrawi from June 2017 to June 2018. A total of 100 knees OA were recruited and 50 healthy subjects as a control group. NLR was significantly higher in knee OA than controls, the mean value was (2.19±0.72) and (1.97±0.88), respectively. Older age, chronic pain, prolong the onset of diagnosis and high NLR were significantly associated with severe OA. Knee OA had higher NLR compared to healthy people. Higher NLR is associated with the severity of knee OA and it is a poor indicator.
Keywords:
Neutrophil-lymphocyte ratio; Osteoarthritis; Bone sclerosis; Osteophytes
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Copyright © 2021 Author(s) retain the copyright of this article. This article is published under the terms of the Creative Commons Attribution Liscense 4.0