Effects of cystic fibrosis on the oral cavity

H. Goumghar * and M. Sidqui

Faculty of Dental Medicine of Casablanca, Hassan II University, Casablanca, Morocco.
 
Review Article
Magna Scientia Advanced Research and Reviews, 2021, 03(02), 061–072
Article DOI: 10.30574/msarr.2021.3.2.0089
Publication history: 
Received on 10 November 2021; revised on 13 December 2021; accepted on 15 December 2021
 
Abstract: 
Cystic fibrosis is a complex, lethal, multi-system autosomal recessive disease resulting from mutations on chromosome 7 that cause dysfunction of an ion channel located on epithelial surfaces. Pulmonary disease is the leading cause of morbidity and mortality in CF. The specific dental manifestations of the disease may result from the condition itself or from complications of treatment. This study presents the dental problems observed in patients with cystic fibrosis and reported in the literature. Particular attention was paid to dental caries, disturbances in the mineralization of hard dental tissues, gingivitis and changes in the content and properties of saliva.
 
Keywords: 
Cystic Fibrosis; Oral health; Dental Caries; Dental Enamel Hypoplasia; Periodontal Diseases; Saliva.
 
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