The effect of aloe vera juice on Aloksan-induced reduction of blood sugar of mice
1 Medical program, Faculty of Medicine, Airlangga University, Surabaya, Indonesia.
2 Department of Histology, Faculty of Medicine, Airlangga University, Surabaya, Indonesia.
3 Department of Medical Physiology and Biochemistry, Faculty of Medicine, Universitas Airlangga, Surabaya, Indonesia.
4 Department of Pharmacology, Faculty of Medicine, Universitas Airlangga, Surabaya, Indonesia.
Research Article
Magna Scientia Advanced Research and Reviews, 2024, 12(02), 333-336
Article DOI: 10.30574/msarr.2024.12.2.0212
Publication history:
Received on 01 November 2024; revised on 14 December 2024; accepted on 17 December 2024
Abstract:
Aloe vera is one of the plants that has many properties. One of the widely used Aloe vera preparations is processed into Aloe vera juice which has benefits for the body if consumed. One of the benefits of Aloe vera juice can lower blood sugar in the body due to the phytochemical content contained therein such as flavonoids, glucomannan and vitamins.
Objective: Analyzing Aloe vera juice at doses of 200 mg/KgBB, 300mg/KgBB and 400mg/KgBB in lowering blood sugar and seeing the most effective dose in mice injected with alloxan.
Methods: Quantitative research conducted by experimental methods in vivo on Mus musculus mice with post test control group design. Results: Kruskal-Wallis test analysis on blood sugar reduction showed a significant decrease in the group given Aloe vera with a p value of 0.015 (P < 0.05).
Conclusion: Aloe vera at a dose of 400mg/Kg BB is proven to reduce blood sugar in mice induced by alloxan.
Keywords:
Aloe vera; Juice; Alloxan; Blood sugar; Hyperglycemia
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