The chemistry of the Kossel’s test for purine bases
Organic Chemistry Department, Faculty of Chemistry, National Autonomous University of Mexico, Mexico City (CDMX), Mexico.
Review Article
Magna Scientia Advanced Research and Reviews, 2021, 01(02), 018-023
Article DOI: 10.30574/msarr.2021.1.2.0001
Publication history:
Received on 02 January 2021; revised on 09 January 2021; accepted on 11 January 2021
Abstract:
Albrecht Kossel discovered the purine adenine and the pyrimidine thymine. He extended the murexide test for uric acid to adenine, guanine, hypoxanthine and xanthine. Since the structural differences in these compounds alter the pathways in these tests, we disclosed the reaction course in these assays. We provide the reaction sequence from the bi-annular base to the final product, the colored sodium purpurate.
Keywords:
Alloxan; Degradation; Oxidation; Purpuric acid; Reactive intermediates; Uramil
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