The Sero-Prevalance of Syphilis among Blood Donors in District Mardan, A comprehensive comparative analysis and blood group correlation with findings across different cities

Furqan Ul Haq 1, *, Asfandiyar Khan Mohmand 2, Qazi Muhammad Farooq Wahab 3, Waqar Ali Shah 4, Muhammad Saad Waqas 5, Zakir Ulllah Khan 6, Attaullah Shah 7, Ijaz Hussain 8, Kashif Ali 9, Numan Salih 10, Areeba Inam Khan 11, Ahad Nawaz 12, Aisha Maqbool 13 and Jibran Ikram 14

1 Radiation Oncology Department, Shifa International Hospital, Islamabad, Pakistan.
2 Internal Medicine Department Park Slope Cardiology Center, Brooklyn.
3 Internal Medicine Department, Khyber Teaching Hospital, Peshawar, KP, Pakistan.
4 Internal Medicine Department, Saidu Teaching Hospital, KP, Pakistan.
5 Pathology Department, Khyber Girls Medical College, Peshawar, Pakistan.
6 Dermatology Department Hayatabad Teaching Hospital, Peshawar, Pakistan.
7 Demonstrator at Gajju Khan Medical College, Sawbi, KP, Pakistan.
8 Intensive Care Unit Department, Advance International Hospital Islamabad, Pakistan.
9 Internal Medicine Department, Ayub Teaching Hospital, KP, Pakistan.
10 Internal Medicine Department, Khyber Teaching Hospital, KP, Pakistan.
11 Ayub Medical College Abbottabad, Pakistan.
12 DHQ Hospital MTI Dera Ismail Khan, Pakistan.
13 Ayub Niazi Medical College, Sargodha, Pakistan.
14 Department of Medicine Rahman Medical College Peshawar, Pakistan.
 
Research Article
Magna Scientia Advanced Biology and Pharmacy, 2024, 11(01), 051–057
Article DOI: 10.30574/msabp.2024.11.1.0009
Publication history: 
Received on 08 December 2023; revised on 30 January 2024; accepted on 02 February 2024
 
Abstract: 
The necessity and importance of blood donation well  known like in thalassemia, leukemia, lymphoma, patients on chemotherapy and after massive hemorrhage from trauma etc.but it’s transfusion can also lead to some major health problems like transmission of infectious diseases such as syphilis and so on. To prevent transmission of infectious diseases through blood transfusion its screening is performed everywhere. For this purpose, a research study is carried out during January 2019 to April 2019 at Mardan medical complex and Mardan teaching institute (MMC-MTI) Mardan KP, Pakistan. The specimens were collected from 625 blood donors with 619 males and 06 females. The samples were sent to the serology section of the pathology department for the diagnosis of syphilis through architect syphilis TP. The sero-prevalence of syphilis and the variation of prevalence in the previous and recent study were the objective of this research. It has found that only 06 male individuals are found to have syphilis infection while there is no such case reported in female individuals. So the overall sero-prevalence and sero-prevalence in male individuals were the same as 0.96%. The most positive cases were in the age group 38-74 years of age individuals. Which is the most sexually active age and it is reported that 1.8% of the sero-prevalence is found. The  seroprevalance of syphilis in A- blood group was 5.5%, B+ patients had 1.56%, and with O+ patients it was 1.16%. From the results and analysis, the sero-prevalence of syphilis in the area and population where the study performed are at more risk of syphilis because per annual 0.30 increases is recorded by comparing the recent results with previous studies. As with the passage of time people are educated so we cannot say that it is because of the lack of awareness no also. So the opinion is that the lifestyle, social interaction of people with one another and carelessness in sexual intercourses is the main risk factors responsible for this increase in sero-prevalence of syphilis. 
 
Keywords: 
Syphilis; Blood transfusion; Transfusion related infections; Hematologic infections; District mardan; Homosexuality; Sexually transmitted infections
 
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