Gastro-retentive drug delivery system: A better approach of drug delivery system

Rajiv Kumar 1, *, Rohit Kumar Chopra 1, Harpreet Singh 1, Parminder Nain 2 and RK Dhawan 1

1 Khalsa College of Pharmacy, Amritsar, Punjab, India.
2 Maharishi Markandeshwar University, Mullana, Ambala, Harayana, India.
 
Review Article
Magna Scientia Advanced Biology and Pharmacy, 2021, 04(01), 025–034
Article DOI: 10.30574/msabp.2021.4.1.0045
Publication history: 
Received on 13 August 2021; revised on 23 September 2021; accepted on 25 September 2021
 
Abstract: 
The oral route is the best and most popular route for the administration of drugs in the systemic circulation. There are number of drugs which are given through the oral route. Gastro-retentive drug delivery system is very important system for the drug delivery system. The gastro-retentive drugs prolonged the drug time in the git and also improve their their bioavailability. These are widely used for site specific for the treatment of git disorders and diseases. There are number of approaches for gastro retentive drug delivery system such as floating system, mucoadhesive system, swelling system, high density system etc. In this review we discussed about approaches and various perspectives of gastro retentive drug delivery system.
 
Keywords: 
Gastroretentive drug delivery system; Floating system; Gastric residence time; Mucoadhesive system; Swelling system
 
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